Name: Adam Spong

Theme: Retroviral Infections

OPTION LIST

A	Anti-HIV Ab (Western blot)	I	Integrase
B	Candidiasis	J	Kaposi’s Sarcoma
C	CCR5/CXCR4	K	MIP-1α
D	CD4	L	Reverse Transcriptase
E	CD8	M	Viral load (PCR)
F	CD25	N
G	gp120	O
H	Hairy Leukoplakia	P

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

1. A 43-year-old man with a known history of HIV presents to his doctor with creamy plaques coating his tongue and oral cavity. His symptoms subside after treatment with fluconazole.

2. A 37-year-old woman with a past history of intravenous drug use presents to her GP for her methadone prescription. On examination they note pale rigid lesions on the side of her tongue. Alongside her methadone the GP prescribes aciclovir.

3. In addition to CD4+ T-lymphocyte counts, HIV monitoring is typically assessed through which measurement?

4. Which of the above is a naturally occurring cytokine that is able to inhibit HIV fusion to CD4+ T-lymphocytes?

5. Which viral protein is responsible for the binding or fusion of HIV to human CD4+ T-lymphocytes?

ANSWERS

1. B

2. H

3. M

4. K

5. G